Hélène Carabin, D.V.M., Ph.D.

carabin[1]

Professor

Phone: (405) 271-2229 x48083
Office: The University of Oklahoma Health Sciences Center
801 Northeast 13th Street, Room 309AB
Post Office Box 26901
Email: helene-carabin@ouhsc.edu

Education and Training

  • Post-Doctoral Fellow. Department of Infectious Disease Epidemiology. Imperial College, UK
  • Post-Doctoral Fellow. Wellcome Trust Centre for the Epidemiolgy of Infectious Diseases. Oxford University, UK
  • Ph.D. Department of Epidemiology and Biostatistics, McGill University, Canada
  • M.Sc. Faculté de Médecine Vétérinaire, University of Montreal, Canada
  • D.V.M. Faculté de Médecine Vétérinaire, University of Montreal, Canada

APPOINTMENTS AND POSITIONS:

  • Adjunct Professor of Epidemiology, Department of Epidemiology, Brown University, 2014-present
  • Special Appointment member of Graduate Faculty at Texas A&M University in the department of Veterinary Integrative Biosciences at the College of Veterinary Medicine, Texas A&M University, 2012-present
  • Professor of Epidemiology, 2011-present.
  • Associate Professor of Epidemiology, 2006-2011.
  • Honorary Lecturer. Department of Infectious Disease and Epidemiology. Imperial College, UK, 2006-2009
  • Assistant Professor of Epidemiology, 2002-2006.

 

Link to most Current Publications

Selected Publications (out of 110 peer reviewed articles)

  • Carabin H, Winkler AS, Dorny P. Taenia solium cysticercosis and taeniosis: achievements from the past 10 years and the way forward. PLoS Neglected Tropical Diseases 2017; 11: e0005478.
  • Prabhakaran V, *Drevets DA, Ramajayam G, Babu JJ, Anderson MP, Hanas J, Rajshekhar V, *Oommen A, *Carabin H. Comparison of monocyte gene expression among patients with neurocysticercosis-associated epilepsy, idiopathic epilepsy and controls in South India. *Equal contribution. PLoS NTDs 2017; 11: e0005664.
  • Mera J, Vellozzi C, Hairiri S, Carabin H, Drevets DA, Miller A, Reilley B, Essex W, Lyons L, Leston J, Ward JW. Identification and Clinical management of persons with chronic hepatitis C virus infection – Cherokee Nationm 2012-2015. MMWR Morb Mortal Wkly Rep 2016; 65: 461-6.
  • Carabin H, Millogo A, Cissé A, Gabriel S, Sahlu I, Dorny P, Bauer C, Ouédraogo J-B, Tarnagda Z, Cowan LD, Ganaba R. Prevalence of and factors associated with human cysticercosis in 60 villages of three provinces of Burkina Faso. PLoS Neglected Tropical Diseases 2015; 9(11): e0004248
  • John CC, Carabin H, Montano SM, Bangira P, Zunt JR, Peterson PK. Global research priorities for infections that affect the nervous system. Nature 2015; 527: S178-86.
  • Carabin H, Ndimubanzi PC, Budke C, Nguyen H, Cowan LD, Qian Y-J, Stoner JA, Rainwater L, Dickey M. Clinical manifestations associated with neurocysticercosis: A systematic review. PLoS Neglected Tropical Diseases 2011; 5(5): e1152

RESEARCH INTERESTS:

  • Epidemiology of infectious diseases, especially zoonotic infections
  • Using the One Health concept to better understand and control zoonoses
  • Assessment of the global burden of parasitic infections
  • Design and statistical analyses of clustered data
  • Application of Bayesian methods to address measurement error and clustering

Current projects as PI:

  • Using Host Responses to Neurocysticercosis to Develop Novel, Brain-imaging Free Diagnostics: a US-India Partnership. This R01 project aims at developing peripheral blood makers for the diagnosis of neurocysticercosis in India. It also includes the development of local capacity to run and analyze Electrospray Ionization mass spectrometry (ESI-MS) and to develop monocyte tissue models of cysticercosis infection. This work is a collaboration among the Department of Biostatistics and Epidemiology, the Section of Infectious diseases and the department of Biochemistry and Molecular Biology at the OUHSC, the Department of Neurosciences at Christian Medical College, Vellore, India and Centre for Cellular and Molecular Platforms in Bangalore, India. Funded under the Brain Disorders in the Developing world: Research Across the Lifespan program by the National Institute of Neurological Disorders and Stroke (NINDS) and the Fogarty International Center (FIC) (R01NS098891).
  • Hepatitis C in Native Oklahoma: optimizing care and setting a path towards elimination of disease and disparity. The goal of this study is to increase the capacity of the Cherokee Nation Health Services (CNHS) to screen for and provide treatment to HCV positive tribal members in the Cherokee Nation as well as understand risk factors for infection. The ultimate goal is to develop educational and clinical programs to eliminate HCV from the CNHS. I serve as the director of the epidemiology, outcomes and statistics team. This is a collaboration among the Department of Biostatistics and Epidemiology and the Section of Infectious diseases at the OUHSC, CNHS and the Center for Infectious Disease Modeling and Analysis at Yale University. Funded by the Gilead Foundation (MPI: Douglas Drevets, Hélène Carabin, Joge Mera).

Current projects as co-investigator or consultant:

  • Oklahoma Shared Clinical and Translational Resources (OSTCR). The overall OSCTR mission is to serve as a catalyst for clinical research which improves health for underserved and underrepresented populations living in rural areas, to improve patient outcomes of these individuals, and to provide these resources to launch new independent IDeA investigator careers. The OSCTR will provide coordination and assistance to investigators in every aspect of clinical and translational research. I serve as the Director of the Novel Methodologies Unit of the Biostatistics, Epidemiology and Research Design Key Component Activity. Funded by the NIH/NIGMS (U54 GM104938, PI: Judith James).
  • Microbial Ecologies of Indigenous communities. This study aims at comparing the gut microbiome from extant traditional peoples to those from urban-industrialized populations to assess if a more “sanitized” lifestyle may have adversely changed our relationship with microbiomes. My role is to develop the design for data collection in Burkina Faso. Funded by the National Institute of General Medical Sciences R01GM089886. (PI: Cecil Lewis)
  • Cysticercosis Network for Sub-Saharan Africa. This study aims at developing an interdisciplinary research platform integrating basic and epidemiological research, capacity building and international networking. Four African partners - one in Mozambique (M), two in Tanzania (T) and one in Zambia (Z) - and two German partners (both TU Munich) are involved and linked with an international advisory board including OUHSC. My role is to lead the epidemiology taskforce for the network.  Funded by the Federal Ministry of Education and Research of Germany. (MPI: Helena Ngowi and Andrea S Winkler).