Parent Page: Departments & Centers id: 26023 Active Page: Yan Daniel Zhaoid:26286
Yan Daniel Zhao

Associate Dean for Research & Presidential Professor

Yan Daniel Zhao, Ph.D.

Contact Information

Phone: (405) 271-2229, x47837

Office: Hudson College of Public Health

801 NE 13th St, Room 327

Post Office Box 26901

Oklahoma City, OK 73104



Daniel Zhao, is Professor of Biostatistics and Associate Dean for Research at the Hudson College of Public Health in the University of Oklahoma (OU) Health Sciences Center. He also serves as the Associate Director of Biostatistics and Research Design Shared Resource at the Stephenson Cancer Center. He is a current member of the NCI Gynecologic Cancers Steering Committee (GCSC) Cervical Cancer Task Force. Dr. Zhao has worked in the pharmaceutical industry for over eight years before he returned to the academia.  His research interests include collaborative biomedical research as a biostatistical contributor as well as independent statistical research.  His statistical research areas include design and analysis of clinical trials, group sequential and adaptive designs, nonparametrics, longitudinal data analysis, Bayesian modeling, and statistical disclosure control. He has published over 120 publications in biomedical and statistical journals.  He is the current Associate Editor for the Journal of Pharmaceutical Statistics and past Associated Editor for the Journal of Statistics in Biopharmaceutical Research.  Dr. Zhao is passionate in teaching and has received the Outstanding Faculty Award for Teaching and Mentoring and the Dean’s Master Teacher Award.  Dr. Zhao also holds the President’s Associates Presidential Professorship.



  • PhD, Statistics, Iowa State University, 2002
  • MS, Statistics, Iowa State University, 1998
  • BS, Mathematics, Peking University, 1996



  • Professor, Department of Biostatistics and Epidemiology, OUHSC, 2019–present
  • Associate Professor, Department of Biostatistics and Epidemiology, OUHSC, 2011–2019
  • Associate Professor, Department of Clinical Sciences and Simmons Cancer Center, University of Texas Southwestern Medical Center at Dallas, 2010–2011
  • Sr. Research Scientist, Eli Lilly and Company, 2006–2010
  • Research Scientist, Eli Lilly and Company, 2004–2006
  • Sr. Statistician, Eli Lilly and Company, 2002–2004


  • BSE 6563 Longitudinal Data Analysis
  • BSE 6643 Survival Data Analysis
  • BSE 6663 Analysis of Multivariate Data
  • BSE 6960 Directed Readings
  • BSE 6980 Research for Doctoral Dissertation


Research Interests:

  • Multiple testing and adaptive designs in clinical trials
  • Sample size and power calculations for nonparametric tests
  • Design, monitoring, analysis, and reporting of clinical trial data
  • Design and analysis issues in misclassified data
  • Adaptive designs for clinical trials with sensitive subgroups of patients
  • Collaborative projects in biology and medicine


Link to Dr. Zhao's current publications

Select publications:

  1. Schneider, Benjamin; Hiers, Shelley; Currier, G.; Kadioglu, Onur; Johnston, Sarah; Zhao, Daniel; Esteban Florez, Fernando; Khajotia, Sharukh. Assessment of Streptococcus mutans biofilms on orthodontic adhesives over 7 days. Am J Orthod Dentofacial Orthop. 2021;160(1):50-57. doi:10.1016/j.ajodo.2020.03.026
  2. Ahmed, Rebaz; Muralidharan, Ranganayaki; Srivastava, Akhil; Johnston, Sarah; Zhao, Daniel; Ekmekcioglu, Suhendan; Munshi, Anupama; Ramesh, Rajagopal. Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells. Cancers (Basel). 2021;13(2):166. doi:10.3390/cancers13020166
  3. Elayapillai, Suganthapriya; Benbrook, Doris; Bieniasz, Magdalena; Wang, Lin; Pathuri, Gopal; Isingizwe, Zitha; Kennedy, Amy; Zhao, Daniel; Lightfoot, Stanley; Hunsucker, Lauri; Gunderson, Camille. Potential and mechanism of mebendazole for treatment and maintenance of ovarian cancer. Gynecol Oncol. 2021;160(1):302-311. doi:10.1016/j.ygyno.2020.10.010
  4. McGrew, Kaitlin; Garwe, Tabitha; Jafarzadeh, S.; Drevets, Doug; Zhao, Daniel; Williams, Mary; Carabin, Hélène. Misclassification Error-Adjusted Prevalence of Injection Drug Use Among Infective Endocarditis Hospitalizations in the United States: A Serial Cross-Sectional Analysis of the 2007-2016 National Inpatient Sample. Am J Epidemiol. 2021;190(4):588-599. doi:10.1093/aje/kwaa207
  5. Homco, Juell; Carabin, Hélène; Nagykaldi, Zsolt; Garwe, Tabitha; Duffy, F.; Kendrick, David; Martinez, Sydney; Zhao, Daniel; Stoner, Julie. Validity of Medical Record Abstraction and Electronic Health Record–Generated Reports to Assess Performance on Cardiovascular Quality Measures in Primary Care. JAMA Netw Open. 2020;3(7):e209411. doi:10.1001/jamanetworkopen.2020.9411