Chao Xu, Ph.D.

Phone: (405) 271-2229, x48054

Office: Hudson College of Public Health

801 Northeast 13th Street, Room 321

Post Office Box 26901

Oklahoma City, Oklahoma 73104

Email: Chao-Xu@ouhsc.edu

Dr. Chao Xu is an Assistant Professor at the University of Oklahoma Health Sciences Center. He is a member of the Stephenson Cancer Center Biostatistics and Research Design Shared Resource. He received his PhD in Biostatistics from Tulane University, US. He has a broad background in statistical genetics, biostatistics, bioinformatics, and genetic epidemiology, with specific training and expertise in genetic and genomic studies of complex diseases, such as the osteoporosis and cancer.

Education:

• PhD, Biostatistics, Tulane University, 2018
• MS, Systems Engineering, University of Shanghai for Science and Technology, 2011
• BS, Management Information System, Jiangsu University of Science and Technology, 2008

Appointments:

• Assistant Professor, Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, 2018–present

Teaching:

• BSE 5023 Computer Applications in Public Health
• BSE 5663 Analysis of Frequency Data
• BSE 6323 Molecular Genetic Epidemiology
• BSE 6980 Research for Doctoral Dissertation

Research Interests:

• Statistical genetics
• High-dimensional statistics
• Bioinformatics
• Genetic epidemiology
• Research design and data analysis in neurology and cancer studies
• Statistical methods for genetic study
• Interaction between human microbiome and environment exposures

Link to Dr. Xu's current publications

Select publications:

1. Wang, Kuan-Song*; Yu, Gang*; Xu, Chao*, Meng, Xiang-He*, et al. Accurate Diagnosis of Colorectal Cancer Based on Histopathology Images Using Artificial Intelligence. BMC Medicine, 2021, 19(1): 76. doi: 10.1186/s12916-021-01942-5 *co-first author
2. Xu, Chao; Zhang, Ruiyuan; Shen, Hui; Deng, Hong-Wen. Medium-coverage DNA sequencing in the design of the genetic association study. European Journal of Human Genetics, 2020, 28(10):1459-1466. doi: 10.1038/s41431-020-0656-2.
3. Khattab, Mohamad; Prodan, Calin; Vincent, Andrea; Xu, Chao; Jones, Kellie; Thind, Sharanjeet; Rabadi, Meheroz; Mithilesh, Shubhada; Mathews, Eleanor; Guthery, Leslie; Dale, George; Kirkpatrick, Angelia. Increased procoagulant platelet levels are predictive of death in COVID-19. Geroscience. 2021;1-11. doi:10.1007/s11357-021-00385-3
4. Liu, Mingyang; Zhang, Yuqing; Yang, Jingxuan; …; Xu, Chao; Bronze, Michael S; Houchen ,Courtney W; Li, Ming. Zinc Dependent Regulation of ZEB1 and YAP1 Co-activation Promotes EMT Plasticity and Metastasis in Pancreatic Cancer. Gastroenterology. 2021, 160(5): 1771-1783 doi: 10.1053/j.gastro.2020.12.077.
5. Rao, Chinthalapally V; Xu, Chao; Farooqui, Mudassir; Zhang, Yuting; Asch, Adam S; Yamada, Hiroshi Y. Survival-Critical Genes Associated with Copy Number Alterations in Lung Adenocarcinoma. Cancers (Basel), 2021, 13(11):2586. doi: 10.3390/cancers13112586.